Aspectos clínicos e sociodemográficos dos casos de Síndrome Respiratória Aguda Grave no sul do Brasil
DOI:
https://doi.org/10.17058/reci.v13i3.17903Resumo
Justificativa e objetivos: comparar, entre os anos de 2020 e 2021, os aspectos clínicos e sociodemográficos dos indivíduos com Síndrome Respiratória Aguda Grave (SRAG) notificados em uma região de saúde do interior do Rio Grande do Sul. Métodos: estudo transversal descritivo, realizado de março de 2020 a outubro de 2021. Foram analisadas variáveis clínicas e sociodemográficas de indivíduos com sintomas de SRAG, comparadas através de análises descritivas, univariadas, conforme o ano de notificação. Resultados: foram notificados 4.710 casos com SRAG; 53,4% foram SRAG relacionados à COVID-19 em 2020 e, 87,5%, em 2021 (p<0,001). Comparando os anos 2020 e 2021, o perfil sociodemográfico modificou quanto faixa etária, cor da pele e escolaridade (p<0,001). Quanto aos aspectos clínicos, houve redução da prevalência de condições de saúde preexistente, exceto obesidade, alterações nos sinais e sintomas relatados e diminuição de internações hospitalares e na Unidade de Terapia Intensiva. Conclusão: as mudanças no perfil podem refletir o efeito das diferentes variantes e o início da imunização para SARS-CoV-2.
Downloads
Referências
Bedretchuk G, Hubie APS, Cavalli LO. Perfil sociodemográfico do paciente acometido por Síndrome Respiratória Aguda Grave: um estudo retrospectivo de nove anos. FAG JOURNAL OF HEALTH (FJH). 2019; 1(4), 67–78. https://doi.org/10.35984/FJH.V1I4.150
Niquini RP, Lana RM, Pacheco, AG. SRAG por COVID-19 no Brasil: descrição e comparação de características demográficas e comorbidades com SRAG por influenza e com a população geral. Cadernos de Saúde Pública. 2020; 36(7), e00149420. https://doi.org/10.1590/0102-311X00149420
Marinho MF. Semelhanças e diferenças na interpretação dos dados sobre SG, SRAG e COVID-19: SIM, SIVEP-GRIPE e cartórios de Registro Civil. Planejamento e Gestão, 2, 112. 2021. https://www.rets.epsjv.fiocruz.br/sites/default/files/arquivos/biblioteca/covid-19-volume2.pdf
Ministerio da Saúde. COVID-19 NO BRASIL Disponível em: https://infoms.saude.gov.br/extensions/covid-19_html/covid-19_html.html
Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clinical Immunology (Orlando, Fla.). 2020; 215, 108427. https://doi.org/10.1016/J.CLIM.2020.108427
WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data. (n.d.). Retrieved May 20, 2022, from https://covid19.who.int/
Zhou B, Thao TTN, Hoffmann D, et al. SARS-CoV-2 spike D614G change enhances replication and transmission. Nature. 2021; 592:7852, 592(7852), 122–127. https://doi.org/10.1038/s41586-021-03361-1
Rearte A, Baldani AEM, Barbacena Barbeira P. Características epidemiológicas de los primeros 116 974 casos de Covid-19 en Argentina, 2020 TT - Epidemiological characteristics of the first 116 974 cases of COVID-19 in Argentina, 2020. Rev. Argent. Salud Publica. 2020; 12(Suplemento Covid-19), 1–9. http://rasp.msal.gov.ar/rasp/articulos/vol12supl/SS-Reartee5.pdf
Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine. 2020; 382(18), 1708–1720. https://doi.org/10.1056/NEJMOA2002032/SUPPL_FILE/NEJMOA2002032_DISCLOSURES.PDF
Marcolino MS, Ziegelmann PK, Souza-Silva MVR, et al. Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry. International Journal of Infectious Diseases. 2021; 107, 300–310. https://doi.org/10.1016/j.ijid.2021.01.019
Casas-Rojo JM, Antón-Santos JM, Millán-Núñez-Cortés J, et al. Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del Registro SEMI-COVID-19. Revista Clínica Española. 2020; 220(8), 480–494. https://doi.org/10.1016/J.RCE.2020.07.003
Souza TA de, Nunes VM de A, Nascimento ICS do, et al. Vulnerabilidade e fatores de risco associados para Covid-19 em idosos institucionalizados. Revista Eletrônica Acervo Saúde. 2021; 13(2), e5947–e5947. https://doi.org/10.25248/REAS.E5947.2021
Nonaka CKV, Gräf T, Barcia CA de L, et al. SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, Northeast Brazil, February 2021. International Journal of Infectious Diseases. 2021; 111, 47–54. https://doi.org/10.1016/J.IJID.2021.08.003
Richardson S, Hirsch JS, Narasimhan M, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 323(20), 2052–2059. https://doi.org/10.1001/JAMA.2020.6775
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020; 395(10229), 1054–1062. https://doi.org/10.1016/S0140-6736(20)30566-3
Barnes CO, Jette CA, Abernathy ME, et al. SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature. 2020; 588:7839, 588(7839), 682–687. https://doi.org/10.1038/s41586-020-2852-1
Amirfakhryan H, Safari F. Outbreak of SARS-CoV2: Pathogenesis of infection and cardiovascular involvement. Hellenic Journal of Cardiology. 2021; 62(1), 13–23. https://doi.org/10.1016/j.hjc.2020.05.007
Guo W, Li M, Dong Y. Diabetes is a risk factor for the progression and prognosis of COVID ‐19. Diabetes/Metabolism Research and Reviews. 2020; 36(7). https://doi.org/10.1002/dmrr.3319
Yang Y, Wang L, Liu J. Obesity or increased body mass index and the risk of severe outcomes in patients with COVID-19. Medicine. 2022; 101(1), e28499. https://doi.org/10.1097/MD.0000000000028499
Jia H. Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease. Shock. 2016; 46(3), 239–248. https://doi.org/10.1097/SHK.0000000000000633
Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020; 323(13), 1239. https://doi.org/10.1001/jama.2020.2648
Cordova E, Mykietiuk A, Sued O, et al. Clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 infection in a Latin American country: Results from the ECCOVID multicenter prospective study. PLOS ONE. 2021; 16(10), e0258260. https://doi.org/10.1371/JOURNAL.PONE.0258260
Portella TP, Mortara SB, Lopes R, et al. Temporal and geographical variation of COVID-19 in-hospital fatality rate in Brazil. MedRxiv. 2021.02.19.21251949. https://doi.org/10.1101/2021.02.19.21251949
Docherty AB, Harrison EM, Green CA, et al. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ. 2020; 369. https://doi.org/10.1136/BMJ.M1985
Vena A, Giacobbe DR, Di Biagio A, et al. Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy. Clinical Microbiology and Infection. 2020; 26(11), 1537–1544. https://doi.org/10.1016/J.CMI.2020.07.049
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2023 Jéssica Luíza Beck, Jane Dagmar Pollo Renner, Marcelo Carneiro, Tatiana Schäffer Gregianini, Ana Paula Helfer Schneider, Andréia Rosane de Moura Valim, Lia Gonçalves Possuelo
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
The author must state that the paper is original (has not been published previously), not infringing any copyright or other ownership right involving third parties. Once the paper is submitted, the Journal reserves the right to make normative changes, such as spelling and grammar, in order to maintain the language standard, but respecting the author’s style. The published papers become ownership of RECI, considering that all the opinions expressed by the authors are their responsibility. Because we are an open access journal, we allow free use of articles in educational and scientific applications provided the source is cited under the Creative Commons CC-BY license.