Aspectos clínicos y sociodemográficos de casos de Síndrome Respiratorio Agudo Severo en el sur de Brasil
DOI:
https://doi.org/10.17058/reci.v13i3.17903Resumen
Justificación y objetivos: comparar los aspectos clínicos y sociodemográficos de individuos con SARS notificados en el interior de Rio Grande do Sul en los años 2020 y 2021. Métodos: estudio descriptivo transversal, realizado de marzo de 2020 a octubre de 2021. Se analizaron variables clínicas y sociodemográficas de individuos con síntomas de SARS, comparadas mediante análisis descriptivos univariados, según el año de notificación. Resultados: se notificaron 4.710 casos de SARS; el 53,4% fueron SARS relacionados con COVID-19 en 2020 y el 87,5% en 2021 (p<0,001). Comparando los años 2020 y 2021, el perfil sociodemográfico cambió en cuanto a grupo de edad, color de piel y escolaridad (p<0,001). En cuanto a los aspectos clínicos, hubo reducción en la prevalencia de condiciones de salud preexistentes, excepto obesidad, cambios en los signos y síntomas reportados y reducción en los ingresos hospitalarios y en la Unidad de Cuidados Intensivos. Conclusión: los cambios en el perfil pueden reflejar el efecto de las diferentes variantes y el inicio de la inmunización para el SARS-CoV-2.
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Bedretchuk G, Hubie APS, Cavalli LO. Perfil sociodemográfico do paciente acometido por Síndrome Respiratória Aguda Grave: um estudo retrospectivo de nove anos. FAG JOURNAL OF HEALTH (FJH). 2019; 1(4), 67–78. https://doi.org/10.35984/FJH.V1I4.150
Niquini RP, Lana RM, Pacheco, AG. SRAG por COVID-19 no Brasil: descrição e comparação de características demográficas e comorbidades com SRAG por influenza e com a população geral. Cadernos de Saúde Pública. 2020; 36(7), e00149420. https://doi.org/10.1590/0102-311X00149420
Marinho MF. Semelhanças e diferenças na interpretação dos dados sobre SG, SRAG e COVID-19: SIM, SIVEP-GRIPE e cartórios de Registro Civil. Planejamento e Gestão, 2, 112. 2021. https://www.rets.epsjv.fiocruz.br/sites/default/files/arquivos/biblioteca/covid-19-volume2.pdf
Ministerio da Saúde. COVID-19 NO BRASIL Disponível em: https://infoms.saude.gov.br/extensions/covid-19_html/covid-19_html.html
Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clinical Immunology (Orlando, Fla.). 2020; 215, 108427. https://doi.org/10.1016/J.CLIM.2020.108427
WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data. (n.d.). Retrieved May 20, 2022, from https://covid19.who.int/
Zhou B, Thao TTN, Hoffmann D, et al. SARS-CoV-2 spike D614G change enhances replication and transmission. Nature. 2021; 592:7852, 592(7852), 122–127. https://doi.org/10.1038/s41586-021-03361-1
Rearte A, Baldani AEM, Barbacena Barbeira P. Características epidemiológicas de los primeros 116 974 casos de Covid-19 en Argentina, 2020 TT - Epidemiological characteristics of the first 116 974 cases of COVID-19 in Argentina, 2020. Rev. Argent. Salud Publica. 2020; 12(Suplemento Covid-19), 1–9. http://rasp.msal.gov.ar/rasp/articulos/vol12supl/SS-Reartee5.pdf
Guan W, Ni Z, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine. 2020; 382(18), 1708–1720. https://doi.org/10.1056/NEJMOA2002032/SUPPL_FILE/NEJMOA2002032_DISCLOSURES.PDF
Marcolino MS, Ziegelmann PK, Souza-Silva MVR, et al. Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry. International Journal of Infectious Diseases. 2021; 107, 300–310. https://doi.org/10.1016/j.ijid.2021.01.019
Casas-Rojo JM, Antón-Santos JM, Millán-Núñez-Cortés J, et al. Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del Registro SEMI-COVID-19. Revista Clínica Española. 2020; 220(8), 480–494. https://doi.org/10.1016/J.RCE.2020.07.003
Souza TA de, Nunes VM de A, Nascimento ICS do, et al. Vulnerabilidade e fatores de risco associados para Covid-19 em idosos institucionalizados. Revista Eletrônica Acervo Saúde. 2021; 13(2), e5947–e5947. https://doi.org/10.25248/REAS.E5947.2021
Nonaka CKV, Gräf T, Barcia CA de L, et al. SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, Northeast Brazil, February 2021. International Journal of Infectious Diseases. 2021; 111, 47–54. https://doi.org/10.1016/J.IJID.2021.08.003
Richardson S, Hirsch JS, Narasimhan M, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 323(20), 2052–2059. https://doi.org/10.1001/JAMA.2020.6775
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020; 395(10229), 1054–1062. https://doi.org/10.1016/S0140-6736(20)30566-3
Barnes CO, Jette CA, Abernathy ME, et al. SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature. 2020; 588:7839, 588(7839), 682–687. https://doi.org/10.1038/s41586-020-2852-1
Amirfakhryan H, Safari F. Outbreak of SARS-CoV2: Pathogenesis of infection and cardiovascular involvement. Hellenic Journal of Cardiology. 2021; 62(1), 13–23. https://doi.org/10.1016/j.hjc.2020.05.007
Guo W, Li M, Dong Y. Diabetes is a risk factor for the progression and prognosis of COVID ‐19. Diabetes/Metabolism Research and Reviews. 2020; 36(7). https://doi.org/10.1002/dmrr.3319
Yang Y, Wang L, Liu J. Obesity or increased body mass index and the risk of severe outcomes in patients with COVID-19. Medicine. 2022; 101(1), e28499. https://doi.org/10.1097/MD.0000000000028499
Jia H. Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease. Shock. 2016; 46(3), 239–248. https://doi.org/10.1097/SHK.0000000000000633
Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China. JAMA. 2020; 323(13), 1239. https://doi.org/10.1001/jama.2020.2648
Cordova E, Mykietiuk A, Sued O, et al. Clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 infection in a Latin American country: Results from the ECCOVID multicenter prospective study. PLOS ONE. 2021; 16(10), e0258260. https://doi.org/10.1371/JOURNAL.PONE.0258260
Portella TP, Mortara SB, Lopes R, et al. Temporal and geographical variation of COVID-19 in-hospital fatality rate in Brazil. MedRxiv. 2021.02.19.21251949. https://doi.org/10.1101/2021.02.19.21251949
Docherty AB, Harrison EM, Green CA, et al. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ. 2020; 369. https://doi.org/10.1136/BMJ.M1985
Vena A, Giacobbe DR, Di Biagio A, et al. Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy. Clinical Microbiology and Infection. 2020; 26(11), 1537–1544. https://doi.org/10.1016/J.CMI.2020.07.049
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Derechos de autor 2023 Jéssica Luíza Beck, Jane Dagmar Pollo Renner, Marcelo Carneiro, Tatiana Schäffer Gregianini, Ana Paula Helfer Schneider, Andréia Rosane de Moura Valim, Lia Gonçalves Possuelo
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