Surveillance of neurological syndromes reported at a federal hospital in a context of Zika, Chikungunya and Dengue epidemics

Authors

  • Alessandra Gonçalves Lisbôa Pereira Serviço de Epidemiologia, Hospital Federal dos Servidores do Estado, Rio de Janeiro, RJ, Brasil; e Universidade Estácio de Sá, Rio de Janeiro, RJ, Brasil.
  • Claudia Caminha Escosteguy Serviço de Epidemiologia, Hospital Federal dos Servidores do Estado, Rio de Janeiro, RJ, Brasil.
  • Márcio Renan Vinícius Espínola Marques Serviço de Epidemiologia, Hospital Federal dos Servidores do Estado, Rio de Janeiro, RJ, Brasil.
  • Luísa Corrêa Bergamo Graduação em Medicina, Universidade Estácio de Sá, Rio de Janeiro, RJ, Brasil.

DOI:

https://doi.org/10.17058/reci.v8i3.11936

Abstract

Background and Objectives: The occurrence of neurological manifestations in the context of the circulation of Dengue virus (DENV), Zika(ZIKV) and Chikungunya (CHIKV) in Brazil is a challenge for epidemiological surveillance. This study aims to describe the clinical epidemiological profile of patients reported in a federal hospital with neurological syndromes potentially associated with these etiologies, in 2015 and 2016. Methods: Observational study, with analysis of secondary bases and data collection in medical records and epidemiological surveillance forms. We included cases reported in 2015 and 2016, meeting the criteria: a)neurological syndrome of undetermined originand registry of previous viral infection up to 60 days before neurological symptoms, laboratory confirmed or not; b) neurological syndrome without prior viral infection up to 60 days before neurological symptoms, with laboratory confirmation for DENV, CHIKV and ZIKV in CSF, serum or urine. Variables analyzed: sex, age, race/color, scholarity level, municipality of residence, signs and symptoms, syndromic andetiological diagnosis of the neurological symptoms, place/ length of hospitalization and evolution. Results: 72 cases reported: 61.1% men, median age 37 years, neurological diagnosis of Guillain-Barré syndrome (GBS) 34.7% and meningoencephalitis 31.9%. Thirty-nine cases (54.1%) were classified as associated with arboviruses, 14 of them by laboratory criteria (3 ZIKV, 6 CHIKV, 4 DENV, 1 DENV + CHIKV) and 25 by clinical-epidemiological criteria. In the laboratory confirmed the percentage of meningoencephalitis (57.1%) exceeded SGB (35.7%). Conclusion: The differential diagnosis among arboviruses in this context is a challenge for epidemiological surveillance, highlighting thepredominance of GBS and meningoencephalitis. Keywords: Arbovirus Infections. Encephalitis, Arbovirus. Guillain-Barre Syndrome. Epidemiology

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Published

2018-07-01

How to Cite

Pereira, A. G. L., Escosteguy, C. C., Marques, M. R. V. E., & Bergamo, L. C. (2018). Surveillance of neurological syndromes reported at a federal hospital in a context of Zika, Chikungunya and Dengue epidemics. Revista De Epidemiologia E Controle De Infecção, 8(3), 261-267. https://doi.org/10.17058/reci.v8i3.11936

Issue

Vol. 8 No. 3 (2018)

Section

ORIGINAL ARTICLE

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