Morbimortality and hospitalization cost of patients with sepsis in Brazil, Rio Grande do Sul and Porto Alegre

Abstract

Background and Objectives: Sepsis is a life-threatening organic dysfunction, secondary to the organism's dysregulated response to infection. The criteria for clinical diagnosis are the variation of at least two points in the Sequential Organ Failure Assessment Score (SOFA).The aim of this study was to carry out a survey of the morbidity and mortality rates and hospitalization costs of patients with sepsis in Brazil, Rio Grande do Sul (RS) and Porto Alegre. Methods: A retrospective study based on secondary data obtained from the Departamento de Informática do Sistema Único de Saúde (DATASUS) in three administrative governmental levels from the last 10 years. Results: There was an increase in sepsis mortality in the three demographic regions. In Brazil, sepsis mortality rate in 2006 was 1.10% and in 2015 it was 1.46%, in RS State, in 2006 it was 0.90% and in 2015 it was 1.14% and in Porto Alegre, in 2006 it was 0.72% and in 2015 it was 0.88%. The percentage of hospitalizations because of sepsis also showed an increase. The costs related to hospitalizations are high, reaching in 2016 the average value of R$ 3,669.75, R$ 3,247.69 and R$ 4,281.41 in Brazil, RS and Porto Alegre, respectively. Conclusion: Due to high morbimortality rates, investments in prevention and early diagnosis of sepsis are urgently needed, focusing on patient safety, training a multiprofessional team, and the implementation of care protocols. Keywords: Sepsis. Indicators of Morbidity and Mortality. Hospitalization. Costs and Cost Analysis.