Chikungunya, Zika and Dengue seroprevalence rates among pregnant women in a hospital of southeastern Brazil

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DOI:

https://doi.org/10.17058/reci.v12i2.16978

Keywords:

Chikungunya Fever, Zika Virus Infection, Dengue, Seroepidemiologic Studies.

Abstract

Background and objectives: For decades, dengue outbreaks have been affecting vast territories of the Americas. In 2010’s decade, Chikungunya and Zika virus (CHIKV and ZIKV) emerged as new arboviruses in the region. While several seroprevalence rates have been reported for dengue virus (DENV) infection in Brazil, serological surveys for the latest are scarce. We aimed to evaluate the seroprevalence of CHIKV, ZIKV, and DENV infections in pregnant women at admission to a public maternity hospital of Nova Iguaçu, state of Rio de Janeiro. Methods: A simple questionnaire was applied, containing limited demographic, obstetric, and clinical data, alongside with blood collection. Different commercial test kits, based on enzyme-linked immunosorbent assay (ELISA), were used. Results: Among 349 pregnant women enrolled from July to December 2017, there was a 28.4% seroreactivity for CHIKV, 47.2% for ZIKV, and 88.8% for DENV. Conclusion: These findings reflect the high dengue endemicity scenario and suggest a significant reach of the recent outbreaks of ZIKV and CHIKV infections in the region.  

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References

Puntasecca CJ, King CH, LaBeaud AD. Measuring the global burden of chikungunya and Zika viruses: A systematic review. PLoS Negl Trop Dis. 2021;15(3):e0009055. http://dx.doi.org/10.1371/journal.pntd.0009055

Pomar L, Musso D, et al. Zika virus during pregnancy: From maternal exposure to congenital Zika virus syndrome. Prenat Diagn. 2019;39(6):420-430. https://doi.org/10.1002/pd.5446

Sreekanth R, Venugopal L, et al. Neonatal chikungunya encephalitis. Trop Doct. 2022;52(1):199-201. https://doi.org/10.1177/00494755211063268

Netto EM, Moreira-Soto A, Pedroso C, et al. High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks. MBio. 2017;8(6). http://dx.doi.org/10.1128/mBio.01390-17

Cunha RV, Trinta KS, Montalbano CA, et al. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. PLoS Negl Trop Dis. 2017;11(1):e0005319. http://dx.doi.org/10.1371/journal.pntd.0005319

Slavov SN, Guaragna Machado RR, Ferreira AR, et al. Zika virus seroprevalence in blood donors from the Northeastern region of São Paulo State, Brazil, between 2015 and 2017. J Infect. 2020;80(1):111-115. http://dx.doi.org/10.1016/j.jinf.2019.10.002

Alves LV, Leal CA, Alves JGB. Zika virus seroprevalence in women who gave birth during Zika virus outbreak in Brazil - a prospective observational study. Heliyon. 2020;6(9):e04817. http://dx.doi.org/10.1016/j.heliyon.2020.e04817

Harrison SC. Immunogenic cross-talk between dengue and Zika viruses. Nat Immunol. 2016;17(9):1010-2. http://dx.doi.org/10.1038/ni.3539

Stettler K, Beltramello M, Espinosa DA, et al. Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection. Science. 2016;353(6301):823-6. http://dx.doi.org/10.1126/science.aaf8505

Huzly D, Hanselmann I, Schmidt-Chanasit J, Panning M. High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses. Euro Surveill. 2016;21(16). http://dx.doi.org/10.2807/1560-7917.ES.2016.21.16.30203

Mendoza EJ, Makowski K, Barairo N, et al. Establishment of a comprehensive and high throughput serological algorithm for Zika virus diagnostic testing. Diagn Microbiol Infect Dis. 2019;94(2):140-146. http://dx.doi.org/10.1016/j.diagmicrobio.2019.01.004

Matheus S, Talla C, Labeau B, et al. Performance of 2 Commercial Serologic Tests for Diagnosing Zika Virus Infection. Emerg Infect Dis. 2019;25(6):1153-1160. http://dx.doi.org/10.3201/eid2506.180361

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Published

2022-09-05

How to Cite

Wittlin, B. B., De Almeida, D. V., Marques, B. C. L., Monteiro, C. C., Moreira, L. F. de S., Linhares, J. H. R., Koifman, R. J., de Lima, S. M. B., & Pilotto, J. H. (2022). Chikungunya, Zika and Dengue seroprevalence rates among pregnant women in a hospital of southeastern Brazil. Revista De Epidemiologia E Controle De Infecção, 12(2). https://doi.org/10.17058/reci.v12i2.16978

Issue

Vol. 12 No. 2 (2022)

Section

BRIEF COMMUNICATIONS

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Copyright (c) 2022 Bernardo Bastos Wittlin, Dalziza Victalina De Almeida, Bianca Cristina Leires Marques, Carolina Cipriano Monteiro, Luiz Felipe de Souza Moreira, José Henrique Rezende Linhares, Rosalina Jorge Koifman, Sheila Maria Barbosa de Lima, José Henrique Pilotto

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