Factores de riesgo y distribución espacial asociados con muertes por COVID-19: revisión integrativa
DOI:
https://doi.org/10.17058/reci.v12i1.17124Resumen
Justificación y objetivos: comprender los factores clínico-epidemiológicos y ambientales relacionados con las muertes por COVID-19 y su distribución en el espacio puede servir como subsidio para orientar e implementar acciones de salud más efectivas para poblaciones vulnerables. Así, el objetivo fue sintetizar la evidencia científica relacionada con los factores de riesgo y la distribución espacial de las muertes por COVID-19 en el mundo. Contenido: se trata de una revisión integradora de literatura, donde se formuló la siguiente pregunta orientadora: ¿cuál es la evidencia científica relacionada con los factores de riesgo y distribución espacial de las muertes por COVID-19 en el mundo? Las búsquedas se realizaron en la Scientific Electronic Library Online (SciELO) y en las bases de datos Scopus, Web of Science y National Library of Medicine (PubMed) en junio de 2021. Se consideraron estudios originales, en portugués, inglés o español, sin marco de tiempo, excluyendo estudios con un grupo de edad específico o con una audiencia con comorbilidad específica. Se incluyeron 25 estudios, con hallazgos en diferentes escenarios alrededor del mundo. Factores, como la edad, el sexo, las enfermedades preexistentes se asociaron a las muertes por COVID-19, que tenían una distribución espacial heterogénea y se produjo en condiciones ambientales, socioeconómicas y geográficas propias de estos territorios. Conclusión: la edad igual o mayor a 60 años, el género masculino, las enfermedades cardiovasculares, la diabetes mellitus y las zonas geográficas con mayor contaminación ambiental, mayor densidad poblacional y malas condiciones sanitarias influyeron en la mortalidad por COVID-19.
Descargas
Citas
Luo Y, Yan J, MCClure S. Distribution of the environmental and socioeconomic risk factors on COVID-19 death rate across continental USA: a spatial nonlinear analysis. Environ Sci Pollut Res Int. 2021;28(6):6587-6599. https://doi.org/10.1007/s11356-020-10962-2
Bourgonje AR, Abdulle AE, Timens W et al. A enzima conversora de angiotensina 2 (ACE2), SARS-CoV-2 e a fisiopatologia da doença coronavírus 2019 (COVID-19). J Pathol. 2020; 251(3): 228-248. https://dx.doi.org/10.1002%2Fpath.5471
Wang F, Kream RM, Stefano GB. Sequelas respiratórias e neurológicas de longo prazo de COVID-19. Med Sci Monit. 2020; (26): e928996. https://doi.org/10.12659/msm.928996
World Health Organization – WHO. Coronavirus (COVID-19). 2021.https://www.who.int/emergencies/diseases/novel-coronavirus-2019?adgroupsurvey={adgroupsurvey}&gclid=CjwKCAjwwsmLBhACEiwANqtXMmrZcl2aKpHElX9an_qHYT41RpyIFKPZhMMyPgBwHStMc-DlwreaxoC-e8QAvD_BwE
Parasher A. COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment. Postgrad Med J. 2021;97(1147):312-320. https://doi.org/10.1136/postgradmedj-2020-138577
Boban M. Atualização da nova doença coronavírus (COVID-19) sobre epidemiologia, patogenicidade, curso clínico e tratamentos. Jornal internacional de prática clínica. 2021; (75): 1-7. https://doi.org/10.1111/ijcp.13868
Ministério da Saúde (BR). Boletim Epidemiológico Especial nº 86. Doença pelo coronavírus COVID 19. Semana Epidemiológica 42 (17 a 23/10) de 2021. https://www.gov.br/saude/pt-br/media/pdf/2021/outubro/29/boletim_epidemiologico_covid_86-final-_29out.pdf
Silva EA, Caetano, JM, Teixeira SHO. A distribuição desigual da COVID-19 no espaço intra-urbano. I Seminário Nacional-Urbanismo, Tempo e Espaço. Revista Políticas Públicas e Cidades. 2020;(1):1 https://rppc.emnuvens.com.br/urbanismo/article/view/457/323.
Guan W, Ni Z, Hu Y et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New england Journal of Medicine. 2020;(382):1708-1720. https://www.nejm.org/doi/full/10.1056/nejmoa2002032
Albitar O, Ballouze R, Ooi JP et al. Risk factors for mortality among COVID-19 patients. Diabetes research and clinical practice. 2020;(166):108293-108297. https://doi.org/10.1016/j.diabres.2020.108293
Sorci G, Faivre B, Morand S. Explicando a variação entre os países na taxa de letalidade do COVID-19. Relatórios Científicos. 2020;10(1):18909. https://doi.org/10.1038/s41598-020-75848-2
Mikami T, Miyashita H, Yamada T et al. Risk factors for mortality in patients 22 with COVID-19 in new york city. J Gen Intern Med. 2020;36(1):17-26. https://doi.org/10.1007/s11606-020-05983-z
Kang D, Choi H, Hunkim J et al. Spatial epidemic dynamics of the COVID-19 outbreak in China. International Journal of Infectious Diseases. 2020;(1):96-102. https://doi.org/10.1016/j.ijid.2020.03.076
Mendes KDS, Silveira RCCP, Galvão CM. Use of the bibliographic reference manager in the selection of primary studies in integrative reviews. Texto & Contexto – Enfermagem. 2019;(28): e20170204. https://doi.org/10.1590/1980-265X-TCE-2017-0204
Joanna Briggs Institute. Manual: Methodology for JBI Scoping Reviews. Edição suplementar. Austrália, 2015. https://nursing.lsuhsc.edu/JBI/docs/ReviewersManuals/Scoping-.pdf.
Ouzzani M, Hammady H, Fedorowicz Z et al. Rayyan -a web and mobile app for systematic reviews. Systematic Reviews. 2016;(5):210. https://doi.org/10.1186/s13643-016-0384-4
Page MJ, Mckenzie JE, Bossuyt PM et al. A declaração PRISMA 2020: uma diretriz atualizada para relatar revisões sistemáticas. Systematic Reviews. 2021;(372):71. http://dx.doi.org/10.1136/bmj.n71
Alamdari NM, Afaghi S, Rahimi FS et al. Risk factors for mortality among hospitalized PATIENTS COVID-19 in an important reference center in the Irã. The Tohoku Journal of Experimental Medicine. 2020;252(1):73-84. https://doi.org/10.1620/tjem.252.73.
Alshogran OY, Altawalbeh SM, Al-Azzam SI, et al. Predictors of COVID-19 case fatality rate: Um estudo ecológico. Ann Med Surg. 2021;(65):102319. https://doi.org/10.1016/j.amsu.2021.102319
Baqui P, Bica I, Marra V et al. Ethnic and regional variations in hospital mortality from COVID-19 in Brazil: a cross-sectional observational study. Lancet Glob Health. 2020;8(8):e1018-e1026. https://doi.org/10.1016/S2214-109X(20)30285-0
Berenguer J, Ryan P, Rodríguez-Baño J et al. Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain. Clin Microbiol Infect. 2020; 26(11):1525–1536. https://doi.org/10.1016/j.cmi.2020.07.024
Donamou J, Touré A, Camara AY et al. Fatores preditivos de mortalidade em pacientes com COVID-19 na Guiné: análise dos primeiros 140 casos admitidos em unidade de terapia intensiva. The Pan African medical journal. 2021;(38):205. https://www.panafrican-med-journal.com/content/article/38/205/full/
Garcia WPD, Fumeaux T, Guerci P, et al. Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort. EClinicalMedicine. 2020;(25):100449. https://doi.org/10.1016/j.eclinm.2020.100449
Mallipattu SK, Jawa R, Moffitt R et al. Geospatial Distribution and Predictors of Mortality in Hospitalized Patients With COVID-19: A Cohort Study. Open Forum Infect Dis. 2020;7(10):ofaa436. https://doi.org/10.1093/ofid/ofaa436
Najera H, Ortega-Avila AG. Health and Institutional Risk Factors of COVID-19 Mortality in Mexico, 2020. Am J Prev Med. 2021;60(4):471-477. https://doi.org/10.1016/j.amepre.2020.10.015
Grasselli G, Greco M, Zanella A et al. Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy. JAMA internal medicine. 2020;180(10):1345-1355. http://jamanetwork.com/article.aspx?doi=10.1001/jamainternmed.2020.3539
Surendra H, Elyazar IR, Djaafara BA. Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study. Lancet Reg Health West Pac. 2021;(9):100-108. https://doi.org/10.1016/j.lanwpc.2021.100108
Yu C, Lei Q, Li W et al. Clinical Characteristics, Associated Factors, and Predicting COVID-19 Mortality Risk: A Retrospective Study in Wuhan, China. Am J Prev Med. 2020;59(2):168-175. https://doi.org/10.1016/j.amepre.2020.05.002
Cao Y, Hiyoshi A, Montgomery S. COVID-19 case-fatality rate and demographic and socioeconomic influencers: worldwide spatial regression analysis based on country-level data. BMJ Open. 2020;10(11):e043560. http://dx.doi.org/10.1136/bmjopen-2020-043560
Kathe NJ, Wani RJ. Determinants of COVID-19 Case Fatality Rate in the United States: Spatial Analysis Over One Year of the Pandemic. J Health Econ Outcomes Res. 2021;8(1):51-62. https://doi.org/10.36469/jheor.2021.22978
Kranjac WA, Kranjac D. Decomposing Differences in Coronavirus-related Case-Fatality Rates em Dezessete Nações. Patógenos e Saúde Global. 2021;115(2):100-107. https://doi.org/10.1080/20477724.2020.1868824
Sousa GJB, Garces TS, Cestari VRF et al. Mortality and survival of COVID-19. Epidemiol Infect. 2020;(148):e123. https://doi.org/10.1017/S0950268820001405
Middya AI, Roy S. Geographically varying relationships of COVID-19 mortality with different factors in India. Scientific reports. 2021;11(1):7890. https://doi.org/10.1038/s41598-021-86987-5
Castro MC; KIM S; Barberia L et al. Spatiotemporal pattern of COVID-19 spread in Brazil. Science. 2021;(372):821-826. https://doi.org/10.1126/science.abh1558
Contreras-Manzano A, Guerrero-López CM, Aguerrebere M et al. Municipality-Level Predictors of COVID-19 Mortality in Mexico: A cautionary Tale. Disaster Med Public Health Prep. 2020;(1):1-9. https://doi.org/10.1017/dmp.2020.485
Harris R. Exploring the neighbourhood-level correlates of COVID-19 deaths in London using a difference across spatial boundaries method. Health Place. 2020;(66):102446. https://doi.org/10.1016/j.healthplace.2020.102446
Souris M, Gonzalez JP. COVID-19: COVID-19: Spatial analysis of hospital case-fatality rate in France. Plos One. 2020;15(12):e0243606. https://doi.org/10.1371/journal.pone.0243606.
Rosenthal N, Cao Z, Gundrum J et al. Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19. JAMA Netw Open. 2020;3(12):e2029058.
http://jamanetwork.com/article.aspx?doi=10.1001/jamanetworkopen.2020.29058
Granda EC, Cunha SGS, Silva MF et al. COVID-19 em idosos: por que eles são mais vulneráveis ao novo coronavírus?. Brazilian Journal of Development. 2021;(7):42572-42581. https://doi.org/10.34117/bjdv7n4-630
Wu C, Chen X, Cai Y et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Internal Medicine. 2020;(180):934-943. http://jamanetwork.com/article.aspx?doi=10.1001/jamainternmed.2020.0994
Zhou F, Yu T, Du R et al. Clinical course and risk factors for mortality in adult patients hospitalized with COVID-19 in Wuhan, China: a retrospective study. Lancet. 2020;(395):1054-1062. https://doi.org/10.1016/S0140-6736(20)30566-3
Sharma A, Volgman AS, Michos ED. Sex Differences in Mortality From COVID-19 Pandemic: Are Men Vulnerable and Women Protected?. JACC: Case Reports. 2020;(2):1407-1410. https://dx.doi.org/10.1016%2Fj.jaccas.2020.04.027
Gadi N, Wu S, Spihlman AP et al. What’s sex got to do with COVID-19? Gender-based differences in the host immune response to coronaviruses. Front Immunol. 2020;(11):2147. https://doi.org/10.3389/fimmu.2020.02147
Borges PKO et al. SARS-COV-2 & COVID-19: o vírus, seus aspectos patológicos e suas manifestações respiratórias e extrapulmonares Ponta Grossa: UEPG/PROEX, 2020. https://www2.uepg.br/proex/wp-content/uploads/sites/8/2020/07/Aspectos-patol%C3%B3gicos06-07.pdf
Han Y, Duan X, Yang L et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;(589):270-275. https://doi.org/10.1038/s41586-020-2901-9
Costa IBSS, Bittar CS, Rizk SI et al. O Coração e a COVID-19: O que o Cardiologista Precisa Saber. Arquivos Brasileiros de Cardiologia. 2020;114(5):805-816. https://doi.org/10.36660/abc.20200279
Muniyappa R, Gubbi S. COVID-19 pandemic, coronaviruses, and diabetes mellitus. Am J Physiol Endocrinol Metab. 2020;(318):736-741. https://doi.org/10.1152/ajpendo.00124.2020
Rouquayrol MZ, Silva MG. Rouquayrol Epidemiologia & Saúde. 8. ed. Rio de Janeiro: MedBook, 2018.
Lucena SEF, Moraes RM. Detecção de agrupamentos espaço-temporais para identificação de áreas de risco de homicídios por arma branca em João Pessoa, PB. Boletim de Ciências Geodésicas. Curitiba. 2012;(18):605-623. https://doi.org/10.1590/S1982-21702012000400006
Pereira VHC, Rocha GC, Diniz MTM et Marcos et al. Análise de dependência espacial da taxa de mortalidade por Covid-19 nos municípios brasileiros. Confins. 2021;(52):40509. https://doi.org/10.4000/confins.40509
##submission.downloads##
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2022 Rayanne Alves de Oliveira, Marcelino Santos Neto, Adriana Gomes Nogueira Ferreira, Lívia Maia Pascoal, Janaína Miranda Bezerra, Richard Pereira Dutra, Ana Lúcia Fernandes Pereira
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
The author must state that the paper is original (has not been published previously), not infringing any copyright or other ownership right involving third parties. Once the paper is submitted, the Journal reserves the right to make normative changes, such as spelling and grammar, in order to maintain the language standard, but respecting the author’s style. The published papers become ownership of RECI, considering that all the opinions expressed by the authors are their responsibility. Because we are an open access journal, we allow free use of articles in educational and scientific applications provided the source is cited under the Creative Commons CC-BY license.