Consumo de antimicrobianos durante el período de la pandemia de COVID-19 en macrorregiones específicas de Brasil
DOI:
https://doi.org/10.17058/reci.v14i2.18259Palabras clave:
Acute respiratory infections., Antimicrobials., Brazil., COVID-19., Pharmacovigilance.Resumen
Justificación y Objetivos: El objetivo principal fue analizar el consumo de antimicrobianos (ATMs) sujetos a retención de ingresos con indicaciones para el tratamiento de infecciones respiratorias en Brasil de 2014 a 2021. Métodos: Se trata de un estudio ecológico de diseño mixto. Datos secundarios obtenidos del Sistema Nacional de Gestión de Productos Controlados (SNGPC). Los datos fueron presentados siguiendo la ecuación: número de consumo total de cajeros automáticos para cada macro región de Brasil por año o trimestre / número de residentes para cada macro región por año *1.000 habitantes. Los datos anuales fueron analizados por Prais-Winsten, y trimestralmente analizados por regresión paso a paso automática hacia adelante. Resultados: La región Sur mostró las mayores tasas medias de consumo en comparación con las demás macrorregiones. Para el análisis anual, la proporción de estabilidad, aumento y disminución de ATMs fue similar entre las macrorregiones. En el trimestre se registró aumento en el consumo de Amoxicilina, Amoxicilina+Clavulanato, Azitromicina y Cefalexina, en conjunto, en las regiones Sur, Sudeste y Norte. Conclusión:Nuestros datos revelan un mayor consumo de algunos ATMs durante el período de la pandemia en macro regiones específicas de Brasil, las cinco macro regiones han mostrado diferentes patrones de consumo de ATMs.
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Derechos de autor 2024 Gisele Paludo Polesello, Iraci Lucena Silva Torres, Charles Francisco Ferreira, Douglas Nunes Stanhke, Vera Maria Vieira Paniz, Liciane Medeiros
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