EVALUATION OF THE POTENTIAL FOR PHYCOREMEDIATION OF BETA-BLOCKER DRUGS USING THE MICROALGAE SCENEDESMUS SUBSPICATUS
DOI:
https://doi.org/10.17058/rjp.v14i2.19364Keywords:
Microalgae, Pharmaceuticals, Bioremediation, ScenedesmusAbstract
Currently, the presence of pharmaceutical contaminants in wastewater is increasingly being detected. Due to the complexity of various pharmaceutical compounds, conventional treatment methods have a low success rate and are insufficient in addressing these contaminants. Microalgae-based bioremediation is a practical, sustainable, economical, and environmentally friendly method for treating various pollutants. In this study, the microalga Scenedesmus subspicatus was used to evaluate its phycoremediation potential for a mix of beta-blocker drugs (propranolol and atenolol) added to the cultivation medium. The microalga was cultivated in NPK medium 3 g L-1 with and without an inorganic carbon source, in a shaker incubator, with a photoperiod (16:8). In the experiments, a comparison was made of the phycoremediation with S. subspicatus under analogous conditions without microalgae, corresponding to the effect of hydrolysis and photolysis of the drug mix molecules. The phycoremediation evaluation was performed through ultra-high performance liquid chromatography/tandem mass spectrometry. Evaluations were carried out in triplicate every 7 days for 21 days. The microalga was responsible for the complete removal of the evaluated beta-blockers in 14 days, and the same removal rate was not observed in photolysis or hydrolysis during the evaluated period, indicating that main agent responsible for removal was the microalga. Therefore, it is evident that phycoremediation with S. subspicatus can become an alternative that complements traditional wastewater treatment processes, allowing for the removal of emerging pollutants, such as the beta-blockers analyzed.
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