Prevalencia de COVID-19 entre trabajadores de salud antes y después de la vacunación
DOI:
https://doi.org/10.17058/reci.v14i4.19221Palabras clave:
COVID-19; SARS-CoV-2; trabajadores de la salud; vacuna.Resumen
Justificación y Objetivos: los trabajadores de la salud tienen un alto riesgo de contraer infecciones durante los brotes de enfermedades. Por tanto, el objetivo de este estudio fue determinar la prevalencia de COVID-19 entre profesionales sanitarios vacunados y no vacunados. Métodos: estudio observacional y transversal, que evaluó casos de síndrome gripal ocurridos entre marzo de 2020 y diciembre de 2021 en trabajadores de la salud vacunados y no vacunados con CoronaVac o Astrazeneca en un hospital del extremo sur de Brasil. El estudio incluyó casos de síndrome gripal caracterizados y monitoreados por intuición del sector de salud ocupacional y a los que se les realizaron pruebas diagnósticas por RT-PCR para SARS-CoV-2. Para verificar los factores y las fortalezas de las asociaciones, se utilizó la medida de la Razón de Prevalencia estimada mediante análisis de regresión de Poisson con ajuste de varianza. Resultados: se evaluaron 1.088 casos de síndrome gripal ocurridos en profesionales de la salud entre 2020 y 2021. Al ajustar por sexo, edad, función, sector, tipo de vacuna o diagnóstico previo de COVID-19, la prevalencia de COVID-19 entre los casos profesionales no vacunados fue de 51,5. % (IC 95%: 46,5-56,5) y 32,1% (IC 95%: 25,3-38,8) entre profesionales no vacunados. Además, la vacunación contra COVID-19 redujo la prevalencia de nuevas infecciones en un 33% (RP: 0,67; IC 95%: 0,56-0,81). Conclusión: la vacunación contra COVID-19 redujo significativamente la prevalencia de COVID-19 entre los trabajadores de la salud, independientemente de sexo, edad, sector, función, tipo de vacuna o diagnóstico previo de COVID-19.
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Heinzerling A, Stuckey MJ, Scheuer T, et al. Transmission of COVID-19 to Health Care Personnel During Exposures to a Hospitalized Patient - Solano County, California, February 2020. MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):472-476. doi: https://doi.org/10.15585/mmwr.mm6915e5. PMID: 32298249; PMCID: PMC7755059.
Buonafine CP, Paiatto BNM, Leal FB, et al. High prevalence of SARS-CoV-2 infection among symptomatic healthcare workers in a large university tertiary hospital in São Paulo, Brazil. BMC Infect Dis. 2020 Dec 2; 20(1):917. doi: https://doi.org/10.1186/s12879-020-05662-8. PMID: 33267836; PMCID: PMC7709093.
Nguyen LH, Drew DA, Graham MS, et al. Coronavirus Pandemic Epidemiology Consortium. Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study. Lancet Public Health. 2020 Sep; 5(9):e475-e483. doi: https://doi.org/10.1016/S2468-2667(20)30164-X. Epub 2020 Jul 31. PMID: 32745512; PMCID: PMC7491202.
World Health Organization (WHO. How do vaccines work?. Publicado em 08 de dez. de 2020. Disponível em: https://www.who.int/news-room/feature-stories/detail/how-do-vaccines-work. Acesso em 12/03/2021.
Lurie N, Saville M, Hatchett R, Halton J. Developing Covid-19 Vaccines at Pandemic Speed. N Engl J Med. 2020 May 21; 382(21):1969-1973. doi: 10.1056/NEJMp2005630. Epub 2020 Mar 30. PMID: 32227757.
Lazarus JV, Wyka K, White TM, Picchio CA, Gostin LO, Larson HJ, Rabin K, Ratzan SC, Kamarulzaman A, El-Mohandes A. A survey of COVID-19 vaccine acceptance across 23 countries in 2022. Nat Med. 2023 Feb;29(2):366-375. doi: 10.1038/s41591-022-02185-4. Epub 2023 Jan 9. PMID: 36624316.
Schmidt Fernandes F, de Castro Cardoso Toniasso S, Castelo Branco Leitune J, et al. COVID-19 among healthcare workers in a Southern Brazilian Hospital and evaluation of a diagnostic strategy based on the RT-PCR test and retest for Sars-CoV-2. Eur Rev Med Pharmacol Sci. 2021 Apr;25(8):3365-3374. doi: https://doi.org/10.26355/eurrev_202104_25748. PMID: 33928624.
Van Loon N, Verbrugghe M, Cartuyvels R, et al. Diagnosis of COVID-19 Based on Symptomatic Analysis of Hospital Healthcare Workers in Belgium: Observational Study in a Large Belgian Tertiary Care Center During Early COVID-19 Outbreak. J Occup Environ Med. 2021 Jan 1;63(1):27-31. doi: https://doi.org/10.1097/JOM.0000000000002015. PMID: 32858554; PMCID: PMC7773160.
Algado-Sellés N, Gras-Valentí P, Chico-Sánchez P, et al. Frequency, Associated Risk Factors, and Characteristics of COVID-19 Among Healthcare Personnel in a Spanish Health Department. Am J Prev Med. 2020 Dec;59(6):e221-e229. doi: https://doi.org/10.1016/j.amepre.2020.07.014. Epub 2020 Aug 18. PMID: 33220760; PMCID: PMC7434331.
Al Maskari Z, Al Blushi A, Khamis F, et al. Characteristics of healthcare workers infected with COVID-19: A cross-sectional observational study. Int J Infect Dis. 2021 Jan;102:32-36. doi: https://doi.org/10.1016/j.ijid.2020.10.009. Epub 2020 Oct 8. PMID: 33039607; PMCID: PMC7543901.
Comelli A, Consonni D, Lombardi A, et al. Nasopharyngeal Testing among Healthcare Workers (HCWs) of a Large University Hospital in Milan, Italy during Two Epidemic Waves of COVID-19. Int J Environ Res Public Health. 2021 Aug 19;18(16):8748. doi: https://doi.org/10.3390/ijerph18168748. PMID: 34444497; PMCID: PMC8392643.
Iversen K, Bundgaard H, Hasselbalch RB, et al. Risk of COVID-19 in health-care workers in Denmark: an observational cohort study. Lancet Infect Dis. 2020 Dec;20(12):1401-1408. doi: https://doi.org/10.1016/S1473-3099(20)30589-2. Epub 2020 Aug 3. Erratum in: Lancet Infect Dis. 2020 Oct;20(10):e250. PMID: 32758438; PMCID: PMC7398038.
Toniasso SCC, Fernandes FS, Joveleviths D, et al. Reduction in COVID-19 prevalence in healthcare workers in a university hospital in southern Brazil after the start of vaccination. Int J Infect Dis. 2021 Aug;109:283-285. doi: https://doi.org/10.1016/j.ijid.2021.07.025. Epub 2021 Jul 14. PMID: 34271203; PMCID: PMC8277538.
Angel Y, Spitzer A, Henig O, et al. Association Between Vaccination With BNT162b2 and Incidence of Symptomatic and Asymptomatic SARS-CoV-2 Infections Among Health Care Workers. JAMA. 2021 Jun 22;325(24):2457-2465. doi: https://doi.org/10.1001/jama.2021.7152. PMID: 33956048; PMCID: PMC8220476.
Barrett, E.S., Horton, D.B., Roy, J. et al. Prevalence of SARS-CoV-2 infection in previously undiagnosed health care workers in New Jersey, at the onset of the U.S. COVID-19 pandemic. BMC Infect Dis 20, 853 (2020). https://doi.org/10.1186/s12879-020-05587-2.
Ojanperä H, Ohtonen P, Kanste O, et al. Impact of direct hand hygiene observations and feedback on hand hygiene compliance among nurses and doctors in medical and surgical wards: an eight-year observational study. J Hosp Infect. 2022 Sep;127:83-90. doi: https://doi.org/10.1016/j.jhin.2022.06.007. Epub 2022 Jun 17. PMID: 35724953.
Gómez-Ochoa SA, Franco OH, Rojas LZ, et al. COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes. Am J Epidemiol. 2021 Jan 4;190(1):161-175. doi: https://doi.org/10.1093/aje/kwaa191. Erratum in: Am J Epidemiol. 2021 Jan 4;190(1):187. PMID: 32870978; PMCID: PMC7499478.
World Health Organization (2019). State of the world's nursing 2020: investing in education, jobs and leadership. Geneva, Switzerland: World Health Organization; 2019. 144 p. Available from: https://www.who.int/publications/i/item/9789240003279.
World Health Organization (2020). State of the world’s nursing 2020: investing in education, jobs and leadership. World Health Organization. Geneva,144p. 2020. ISBN 978-92-4-000329-3. Available from: https://www.who.int/publications/i/item/9789240003279.
Firew T, Sano ED, Lee JW, et al. Protecting the front line: a cross-sectional survey analysis of the occupational factors contributing to healthcare workers’ infection and psychological distress during the COVID-19 pandemic in the USABMJ Open 2020;10:e042752. doi: https://doi.org/10.1136/bmjopen-2020-042752.
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